ACS2005年出版33种纸本和电子期刊，每一种期刊都回溯到了期刊的创刊卷，最早的到1879 年。这些期刊涵蓋了24个主要的学科领域：
生化研究方法 药物化学 有机化学 科学训练 普通化学 环境化学 材料学
燃料与能源 植物学 毒物学 食品科学 药理与制药学 物理化学 环境工程学
工程化学 微生物应用生物科技 应用化学 分子生物化学 分析化学 聚合物
无机与原子能化学 资料系统电脑化学 学科应用 农业学
主要有以下期刊:
Accounts of Chemical Research
ACS Chemical Biology—CALL FOR PAPERS!
Analytical Chemistry
I&EC Analytical Edition (1929-1946)
Biochemistry
Bioconjugate Chemistry
Biomacromolecules
Biotechnology Progress—Copublished with
the Am. Inst. of Chem. Engineers
Chemical & Engineering News
Chemical Research in Toxicology
Chemical Reviews
Chemistry of Materials
Crystal Growth & Design
Energy & Fuels
Environmental Science & Technology
Industrial & Engineering Chemistry Research Journal of I&EC (1909-1922)
I&EC (1923-1970)
I&EC Fundamentals (1962-1986)
I&EC Process Design and Development (1962-1986)
I&EC Product Research and Development (1962-1986)
Inorganic Chemistry
Journal of Agricultural and Food Chemistry
Journal of the American Chemical Society
Journal of Chemical & Engineering Data I&EC Chem and Eng Data Series (1956-1958)
Journal of Chemical Information and Modeling
(formerly Journal of Chemical Information and Computer Sciences)
Journal of Chemical Documentation (1961-1974)
Journal of Chemical Theory and Computation
Journal of Combinatorial Chemistry
Journal of Medicinal Chemistry
Journal of Natural Products—Copublished with the Am. Soc. of Pharmacognosy
The Journal of Organic Chemistry
The Journal of Physical Chemistry A
The Journal of Physical Chemistry B The Journal of Physical Chemistry (1896-1996)
Journal of Proteome Research
Langmuir
Macromolecules
Molecular Pharmaceutics
Nano Letters
Organic Letters
Organic Process Research & Development
Organometallics